Suggestions: Take traditional Chinese medicine to clear the heart and soothe the nerves, soothe the nerves in important towns, invigorate qi and nourish blood, improve immunity, invigorate qi and strengthen spleen and treat stomach. Psychoanalysis: Hello, according to the personal situation you provided, it may be because your personality is sensitive and fragile, thoughtful, psychologically stressed and nervous, and you can't relax and calm before going to bed, resulting in insomnia, brain dysfunction, irritability and anxiety. It is a psychogenic problem with neurosis, which can be improved by regular psychotherapy. Long-term mental instability can lead to a variety of physical and mental diseases. Dietary supplements are only an aid, not a major therapeutic effect.
Psychological guidance: I suggest you go to the nearest regular Chinese medicine hospital for examination first, and choose symptomatic Chinese medicine to regulate the body surface symptoms under the guidance of a doctor; At the same time, we should pay attention to the importance of psychological pathogenic factors, go to the nearest regular psychotherapy institution in time for examination and measurement, diagnose the nature and severity of the current symptoms, and make adjustments and improvements through regular psychotherapy. Usually keep your diet light and nutritious, and don't eat spicy food. Guidance: Hello, it is recommended to use vitamin B 1+ oryzanol+Anshen Bunao Liquid for adjustment treatment under the guidance of a doctor. At the same time, be careful not to change your mood too much. It is advisable to eat more foods rich in protein and trace elements. People are animals and belong to the same biology as plants. During the day (5 am to 2 1 p.m.), activities generate energy, and at night (2 1 p.m. to 5 am), cell division begins, transforming energy into new cells, which is a time for human cells to recuperate and bring forth new ones. It's also that people rotate with the earth to the side facing away from the sun. Yin dominates quietness, which is a good time for people to sleep. Only by resting at this time can they have a good physical and mental state. This is the same reason as that babies who sleep a lot grow fat and grow fast, while children who love to sleep are stunted.
Sleep is a major function of health preservation. Health preservation means replacing rotten cells with a large number of healthy cells. If you can't sleep overnight, you won't be able to replace new cells. If you say that one million cells die during the day and only 500,000 cells are replaced in one night, your body will be deficient. After a long time, people will be chaff, like chaff and radish. Why are there centenarians in the world? Because they go to bed on time at 2 1 o'clock every night, the purpose of the operation is to restore the diameter of the spinal canal, but the recovery of paralyzed nerves due to compression depends on the promotion of drugs besides self-repair. Postoperative recovery is acceptable, but some nerves are still in a state of paralysis and shock. If the disease is not recovered optimally within effective treatment, the nerves may atrophy and soften due to long ischemia time, and it is more difficult to recover various functions at this time. Therefore, the key to treatment and recovery lies in early stage.
At present, besides neurotrophic drugs, spinal nerve regeneration pills can be used to excite and activate nerve cells that are paralyzed and shocked after injury, and enhance the conduction between cells to obtain the best recovery of limb function and defecation.
I wish you a speedy recovery! Lumbar surgery only restores the diameter of spinal canal and creates favorable conditions for nerve recovery, but it can't restore the nerve. Besides self-repair, the nerve recovery from compression injury and paralysis depends on the promotion of drugs to get the best recovery state. If the disease can't get the best recovery within the effective treatment period, the nerves may atrophy, soften, degenerate or necrosis due to the long ischemic time, and the recovery of the disease is hopeless. Therefore, the key to treatment and recovery lies in early stage. In addition to neurotrophic drugs, traditional Chinese medicine can be used to enhance and improve the injured part of nerve.
And use nerve regeneration drugs to excite and activate those who are still paralyzed and shocked after operation.
In order to dominate the lower limb function to recover and improve. If you need help, please send a magnetic shock for your guidance. 1, the diet should be regular, soft and chewy food should be selected, and patients with pain caused by chewing should eat.
Never eat fried food, irritating food, seafood products and
Wait; The diet should be nutritious, and you should eat more vitamins and clear fire at ordinary times.
Food; Eat more fresh fruits, vegetables and beans, eat less fat and eat more lean meat, and the food should be light.
2, eat gargle, talk, brush your teeth, wash your face should be gentle, not irritating food, so as not to induce.
Cause by point
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3, pay attention to keep your head and face warm, avoid local freezing and dampness, and don't wash your face with too cold or too hot water; Usually, you should keep your mood stable, not excited, often listen to soft music, feel calm and get enough sleep.
4. Keep happy and avoid mental stimulation; Try to avoid touching the "trigger point"; Regular living, indoor environment should be quiet, clean and fresh air. Appropriate participation in sports, exercise, and enhance physical fitness. Let's start with some professional drugs to repair nerve function, the first kind of nerve growth factor enhancer
Pulverine Potassium Pulverine Potassium is a cognitive enhancer, which is used to treat mild and moderate Alzheimer's disease (AD). It can enhance nerve cell function, stimulate axon growth and improve memory ability by increasing the level of neurotrophic growth factor of damaged or degenerated neurons. It is the first drug to enter the phase III clinical trial for enhancing nerve regeneration.
Acetyl L- Carnitine Acetyl L- Carnitine is a cholinergic agonist, which can actively cross the blood-brain barrier, protect the central and peripheral synapses, improve the level of nerve growth factor and improve the cognitive defects of elderly rats in neurodegenerative and aging models. Currently, it is undergoing phase III clinical trials in the United States.
The second kind of neurotrophic drugs
Ganglioside (GM 1) Ganglioside can promote nerve remodeling (including nerve cell survival, axon elongation and synaptic growth), and play an important role in cell differentiation, development, nerve tissue repair, neuron plasticity and so on.
Brain protein hydrolysate is a new drug to improve brain metabolism, which easily enters brain nerve cells through the blood-brain barrier, affecting their protein synthesis and respiratory chain, enhancing the antioxidant capacity of brain cells, protecting the nervous system from toxic substances, delaying the death of brain cells and promoting their survival.
Cytidine disodium triphosphate injection is a kind of nucleotide drug, which can not only promote the synthesis of protein, but also regulate and promote the synthesis and construction of cell membrane structure of nerve cells, glial cells and blood vessel walls, and can resist the nerve cell injury caused by excitatory amino acids and free radicals, thus having the functions of supporting survival, enhancing activity, delaying death, improving the ability of cells to resist injury and repair, promoting the regrowth of nerve axons, improving the nerve function that dominates blood vessels, and playing an anti-arteriosclerosis role.
Oxiracetam Oxiracetam is a new kind of central nervous system drug which can promote learning and memory ability. Oxiracetam can selectively act on cerebral cortex and hippocampus to activate, protect or promote the functional recovery of nerve cells.
The third kind of drugs that destroy and inhibit axon growth
In the process of nerve injury repair, besides the factors that promote nerve growth, nerve growth inhibitory factors should also be considered. Among them, mature oligodendrocytes can produce many axon growth inhibitors, and primitive oligodendrocytes can also shrink axon growth cones and inhibit axon extension.
Chondroitinase ABC(chABC) can decompose the glycosaminoglycan chain of chondroitin sulfate proteoglycan. Bradbury et al. found that intraspinal administration of chABC can effectively promote axonal regeneration and improve motor and proprioception function of rats after spinal cord injury. Local injection of chABC into the injured focus can promote axonal regeneration and functional recovery in the treatment of spinal cord injury. This discovery has a very attractive prospect in promoting the plasticity of adult central nervous system (CNS) and the recovery of nerve function.
Chondroitin sulfate proteoglycan also has neuroprotective effect. Further discussion on the regulation mechanism of extracellular matrix molecule expression under CNS pathological conditions will provide new ideas for CNS injury repair research. Weakening the inhibitory effect of myelin axon growth is also an effective strategy to promote axon regeneration.
In addition, blocking Ngg, the receptor of myelin-related axon regeneration inhibition, is also an effective strategy, and cAMP, the second messenger, has also been found to weaken the inhibitory effect of these factors.
The fourth category of antioxidants and energy metabolism drugs
Oxidative stress is related to the pathogenesis of many nervous system diseases, including Alzheimer's disease (AD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), Friedrich's ataxia (FRDA), etc. Antioxidants and energy metabolism drugs have been used for neuroprotective treatment of many nervous system diseases.
Edaravone is a free radical scavenger and antioxidant. A large number of research results show that Edaravone can inhibit the peroxidation of brain cells, thus reducing brain edema and tissue damage caused by cerebral ischemia and cerebral hypoxia, and is used for neuroprotective treatment of acute stroke.
Coenzyme Q 10 has two main functions: first, it plays an important role as a nutrient in the process of transforming into energy in mitochondria; Second, it is obviously resistant to lipid peroxidation. The combination of coenzyme Q 10 and vitamin E can increase the productivity of heart and autonomic muscles in FRDA patients and effectively reduce the dilated myocardium in FRDA patients.
Idebenone idebenone is a synthetic coenzyme Q 10 analog, which can improve the neurological function of patients with FRDA in large doses and is well tolerated.
Creatine Creatine may improve mitochondrial dysfunction, stabilize mitochondrial function, protect neurons, and reduce brain atrophy and the formation of nuclear inclusions in HD.
Selegiline Selegiline is a selective monoamine oxidase inhibitor, which can improve the cognitive ability of AD patients by increasing catecholamine, and is mainly used for mild to moderate AD. Selegiline has a certain neuroprotective effect and has been recommended as a neuroprotective drug by Parkinson's disease neuroprotective Committee.
LAX- 10 1 is an inhibitor of phospholipase and cysteine aspartic protease, which may enhance mitochondrial activity, and is now preparing for phase III clinical trials.
The fifth kind of neurotransmitter drugs
Acetylcholinesterase inhibitors (AchEIs), such as tacrine, donepezil, rivastigmine and galanthamine, are approved by FDA for the treatment of mild and moderate AD. Donepezil can also improve the aphasia quotient index of patients with aphasia after stroke.
Nicotinic acetylcholine receptor agonist (nAChR) exists widely in the nervous system, which can improve the cognitive memory impairment of AD through various mechanisms. Stimulating nAChR can improve cognitive memory. Among the various selective nAChR agonists developed, some have entered the clinical trial stage, including GTS-2 1, ABT-4 18, nefixatan and so on.
Thyroid stimulating hormone releasing hormone (TRH) analogue TRH, as a neurotransmitter, can regulate other neurotransmitters and improve learning and memory. TRH analogues such as montetirine, azetirine and portirine have entered clinical trials.
L-dopa L-dopa not only can significantly improve the symptoms of patients, but also has neuroprotective effect, and increases the level of glutathione, which has neurotrophic effect.
Ritalin Ritalin combined with physical therapy can improve the motor function of stroke patients, relieve depression, and improve the thinking activities of patients with traumatic brain injury, which is better than the control group in terms of attention and movement.
Buspirone, a 5-HT receptor agonist, is a 5-HT receptor agonist, which can significantly improve the stability, coordination, articulation and eye movement function of patients with ataxia. Tandospirone is used to treat anxiety and depression, and can improve dysarthria and upper limb symptoms of patients with ataxia.
As a new generation of antidepressants, 5-HT reuptake inhibitor (SSR 1) SSR 1 can block 5-HT reuptake, increase the bioavailable 5-HT in synaptic cleft, and thus enhance 5-HT nerve transmission. Fluoxetine is used to treat severely disabled stroke patients, and their walking function and daily living ability have been improved.
Reboxetine, a selective norepinephrine reuptake inhibitor (NRI), is a new antidepressant. Clinical trials in the treatment of patients with sequelae of stroke have found that finger tapping speed and grip strength are improved.
Memantine, an antagonist of N- methyl -D- aspartic acid (NMDA) receptor, is a non-competitive antagonist of NMDA receptor, which can prevent the development of AD by inhibiting NMDA receptor-mediated excitotoxicity. Memantine has neuroprotective effect, which is not only effective for mild AD, but also can significantly improve the clinical symptoms of severe dementia. When it is combined with AchE inhibitor, it can increase the curative effect and has good tolerance.
The sixth kind of anti-excitotoxic drugs
Riluzole is an excitatory amino acid receptor blocker with potential neuroprotective effect, and it is the only drug approved by FDA for clinical treatment of ALS. Riluzole has a short-term anti-dance action and sustained mental movement speed and behavior in HD patients, but it has no significant effect on delaying the progress of the disease.
Gabapentin is an inhibitor of glutamate synthesis and release, which can delay the muscle weakness and prolong the survival time of ALS patients. However, the results of phase III clinical trial showed that there was no significant difference between the treatment group and the control group. The main cause of cortical cerebellar atrophy is the loss of Purkinje cells in the anterior vermis of cerebellum, which reduces the concentration of GABA in tissues. Gabapentin can effectively alleviate cerebellar symptoms.
Lamotrigine is a drug that can inhibit the release of glutamic acid and aspartic acid, temporarily improve the symptoms of ALS, delay the progress of the disease, and improve the abnormal walking of SCA3 patients.
The seventh class of other drugs
The study of lithium carbonate found that lithium has neurotrophic and neuroprotective effects, protecting granular cells in cerebral cortex, hippocampus and cerebellum. Animal and clinical studies show that lithium can be used to intervene acute brain injury (such as ischemia), spinal cord injury and chronic neurodegenerative diseases (such as AD, PD, HD, etc.).
Statins are the key enzyme inhibitors of cholesterol synthesis in mevalonate pathway, which can reduce the cholesterol content in the body, not only significantly reduce the incidence of ischemic stroke in patients with coronary artery disease, but also have neuroprotective effects independent of their lipid-lowering effects and reduce the occurrence of dementia.
Erythropoietin (EPO) EPO is a neuroprotective or (and) nerve repair drug that has attracted much attention in recent years. In addition to hematopoiesis, it also has the protective effect of nervous system. Drugs such as nerve regeneration factor, mecobalamin and vitamins for nerve injury should only be treated early. If it is early, the combination of medicine+acupuncture+hyperbaric oxygen is the best. Oryzanol, Mecobalamin, Vitamin B 1, Vitamin B 12.