Generally not obvious, patients do not have obvious self-conscious symptoms, with the progress of the disease, the patient's symptoms gradually appear, such as eyelid and facial edema, lower limb ankle edema or edema in the low-hanging part of the body, etc., and some patients may also have pleural effusion, abdominal effusion problems. In addition, some patients may have proteinuria and hematuria of the naked eye, and some may have fatigue, weakness, nausea, anorexia, and increased blood pressure; in severe cases, they may have pain in the renal region, such as lumbar acidity, or they may have pallor and anemia