Syrup extractant refers to concentrated sucrose aqueous solution containing drugs or aromatic substances. The concentrated sugar and directional substances of Tangjiang can mask the bitterness and saltiness of some drugs, which is not a smell, but the drugs are easy to take orally, especially popular with children. Syrup extractant refers to concentrated syrup solution containing drugs or aromatic substances.
High fructose corn syrup:
In fact, this is a newly developed starch syrup, and its sweetness is equal to or higher than sucrose. Because fructose and glucose are sugars of fructose, they are called fruit grape pulp. D- glucose is partially converted into fructose under the action of isomerase and catalyst.
The principle of isomerization is very simple. Glucose syrup with high DE value was decolorized by activated carbon, desalted and degassed by ion exchange, and then the corresponding catalyst or stabilizer was added to complete the isomerization reaction at pH 6.5 ~ 8.5 and temperature 60 ~ 70℃.
For pH value, each enzyme is specific and cannot be selected arbitrarily. The advantage of high fructose corn syrup is that any kind of starch can be used as raw material, regardless of geographical and seasonal conditions. The factory can produce all year round. Rich in raw material resources and cheap, it is produced by enzymatic method. General conditions, simple drying equipment and less investment. Therefore, the production of high fructose corn syrup has developed rapidly.
Preparation of syrup
Hot solution method: weigh sucrose according to the prescription, add appropriate amount of boiling distilled water, heat and stir to dissolve, then add soluble drugs, filter after dissolution, and add appropriate amount of distilled water from the filter to the specified volume.
The advantage of this method is that sucrose raw materials often contain a small amount of protein, which can be solidified by heating, easy to filter, and can kill microorganisms, which is beneficial to preservation. However, attention should be paid to avoid heating rabbits for too long, otherwise the increase of invert sugar will easily lead to fermentation coking and color deepening.
Therefore, it is best to grasp the boundary of 5 minutes after boiling and filter quickly while it is hot. When it is difficult to filter clear syrup, filter AIDS such as filter pulp, talcum powder and egg protein can be used to adsorb impurities, which is helpful for filtration. Plate-and-frame filter press can be used for filtration in mass production.
The method is suitable for simple syrup or syrup containing non-volatile components and heating-stable drugs.
Cold dissolving method: weigh sucrose according to the prescription, dissolve it in distilled water or medicinal solution under stirring at normal temperature (about 200C), filter until it is clean, and collect it.
The advantage of this method is that the finished product is light in color and contains less converted sugar. The disadvantage is that sugar takes a long time to dissolve, so the preparation should strictly require environmental hygiene and personal hygiene to prevent bacterial pollution.
This method is also suitable for simple syrup and syrup that is not suitable for heating, such as syrup containing volatile oil and volatile drugs.
Mixing method: the concentrated solution of the leaching preparation, the drug or the liquid preparation of the drug and the syrup are directly mixed evenly in the solution prepared by this method.