I mention this question is to have their own views and opinions. And it is after a lot of and long-term observation and some experiments.
We see this topic the first feeling is surely this is what a bullshit question, stomach medicine is sure to cure the stomach disease, can not cure the stomach disease that is still called stomach medicine? The first thing you need to do is to ask the question!
In fact, not, the vast majority of existing gastric drugs really can not cure gastric disease. The first thing you need to do is to get your hands on a new one, and you'll be able to do that.
Existing gastroenterology drugs for the stomach have so many categories:
1, antacids, acid inhibitors, such as magnesium aluminum carbonate, omeprazole, etc., its effect is only to neutralize and reduce the secretion of gastric acid, to improve the symptoms of acid reflux.
2, protective agents, such as bismuth gum, bismuth citrate potassium class, it only plays a role in the formation of gel, attached to the stomach surface to protect the role of the gastric mucosa. It's a little bit of anti-ulcer effect.
3, gastric power drugs, such as domperidone, mosapride, etc., to improve and promote gastric peristalsis and emptying.
4, antimicrobials, such as amoxicillin, clarithromycin, etc., just broad-spectrum antibacterial drugs, generally taken through the intestinal absorption, through the blood vessels back to the stomach body to kill bacteria in the gastric tissues, and can only improve part of the inflammation.
The current outpatient medications are mainly of these types. We can see that these drugs are only for the surface symptoms to improve the role, some are only palliative agents. Really cure gastric disease itself is not the role.
Some people may say that there are a lot of proprietary Chinese medicines, tell you, there is no stomach disease in Chinese medicine, only the spleen and stomach and dietary injuries to the stomach, all the stomach disease of proprietary Chinese medicines are almost all the gas and stomach this kind of function, to put it bluntly starting point of the role of conditioning, did not get on the side of the treatment of gastric diseases.
After all, almost all of the current gastric medicines are just medicines to alleviate gastric problems, not medicines to cure gastric problems.
This explains why so many patients are not cured for a long time. The reason for this is to know it.
Of course, I'm not saying this so that we can blame the hospitals and doctors, who also want to help patients get well, but there is no medicine available. The problem lies in the fact that the relevant medical research work has not been followed up, and the right stomach medicine has not been developed. It is the same all over the world. There is no good medicine in any country. The U.S., Europe, Japan, Russia and China are using the same drugs.
We don't have to be anxious, according to my understanding, researchers should have a big breakthrough in the last one or two years. The cure for gastric problems will be simple and cheap by then. The first thing you need to do is to get your hands dirty! The drug will be here soon!
First of all, I need to tell you that there are many kinds of stomach medicines, there are many kinds of stomach diseases, different stomach diseases need to use different stomach medicine. You can't use all the stomach medicines uniformly in the treatment of gastric diseases, which is a very blind and generalized approach.
Xiao Ke first to say for everyone in the end of the commonly used gastric drugs are what?
1. Gastric mucosal protection drugs: mainly magnesium aluminum carbonate, bismuth pectin, bismuth potassium citrate, aluminum thioglycollate, bismuth subcarbonate, aluminum hydroxide, mazillions of dollars, Rebapat and so on, these medicines have a very good gastric mucosal protection, can be in the gastric mucosal surface formation of a layer of effective protective film, to protect the gastric mucosal from gastric acid, bile and other damaging factors of damage to the damage.
Gastric mucosal protection drugs are mainly used for erosive gastritis, gastric ulcer, duodenal ulcer, reflux esophagitis, bile reflux gastritis and other gastric diseases.
2. Acid-suppressing drugs: can be divided into two kinds of proton pump inhibitors and H2 receptor antagonists, proton pump inhibitors to omeprazole, rabeprazole, pantoprazole, lansoprazole-based, and H2 receptor antagonists are based on Ranitidine, Famotidine, Nizatidine-based, both of these two types of drugs have a very good acid suppression, can inhibit the excessive secretion of gastric acid, so as to avoid the destruction of the mucous membrane barrier of the stomach for the acid and the esophagus, bile reflux esophagitis, bile reflux gastritis and other gastric diseases. The destruction of the gastric mucosal barrier and the esophageal mucosa.
Acid-suppressing drugs are commonly used in: reflux esophagitis, gastroesophageal reflux disease, peptic ulcer, combined treatment of Helicobacter pylori eradication, Zuo'ai syndrome, but also used for gastric acidity caused by abdominal pain, acid reflux, heartburn and other symptoms of relief.
3. Promote gastrointestinal peristalsis drugs: can effectively promote gastrointestinal peristalsis, relieve the gastrointestinal peristalsis dysfunction and gastric emptying obstacles caused by abdominal distension, indigestion and other symptoms, commonly used drugs are cisapride, moxapride, itopride, domperidone, trimetoprim and so on.
Promote gastrointestinal peristalsis drugs commonly used: chronic gastritis caused by bloating and indigestion, atrophic gastritis, functional dyspepsia and other diseases. It can also be used to relieve bloating and abdominal pain after overeating and overfeeding.
Many people have this experience, after eating a meal, or get up early in the morning, feel full stomach, a burst of acidic flavor gush to the throat, and even the mouth.
Along with this "sour" acid reflux experience, some people will have heartburn, heartburn, throat swelling and other feelings.
With frequent acid reflux and gastrointestinal discomfort, most people are likely to choose to take a common stomach medication, a proton pump inhibitor (PPI).
You may think it's strange, but that's just a general term for them, specifically the common clinical drugs: Omeprazole , Lansoprazole , Pantoprazole , Rabeprazole and so on, isn't it familiar?
All of these drugs have one ****ing effect, which is to inhibit gastric acid secretion.
The principle of treatment is also very simple: you regurgitate stomach acid? Then reduce stomach acid, so that the symptoms do not ease a lot.
Many people therefore take them as a regular medicine, take some if they feel acid reflux, and the effect seems to be immediate.
But just in May 2019, a large study involving 200,000 people revealed to us the relationship between long-term dependence on such drugs, and the risk of stomach cancer, kidney disease, cardiovascular disease, and the results may make you shudder.
Common acid-suppressing drugs: increased risk of gastrointestinal cancers
Such a study was published in the British Medical Journal (BMJ), one of the world's four prestigious leading medical journals, led by the University of Washington School of Medicine.
Screenshot of the study
The scientists pulled medical records from the VA database for the period July 2002-June 2004, and ended up screening 214,467 patients who took stomach pills.
Of these, 157,625 took a prescribed proton pump inhibitor (PPI), and another 56,842 took an acid-suppressing drug called an H2 receptor antagonist (e.g., cimetidine, ranitidine, etc.).
Over 10 years of follow-up, there were about 45 more deaths per 1,000 deaths compared to patients taking H2 receptor antagonists (342 per 1,000), which equates to about 45 deaths per 1,000, which is the equivalent of putting the risk of death by 17% .
Among patients taking proton pump inhibitors, 38.7% of deaths were related to cardiovascular disease, 28.6% to neoplasms, and 13.8% to genitourinary disease.
The researchers further refined their analysis and found that patients taking proton pump inhibitors had an increased risk of dying from tumors, genitourinary disease, and cardiovascular disease by 18%, 94%, and 25%, respectively, which was increased by additional deaths from gastrointestinal cancers and additional deaths from cardiovascular disease. strong> increased by 41% and the risk of death from chronic kidney disease more than doubled.
On top of that, the study found that more than half of patients taking proton pump inhibitors didn't really have a medical need for them (and could have done without them), and deaths were much more common in this group of patients.
And these risks increased the longer the duration of proton pump inhibitor use, even at low doses.
Dr. Al-Aly, one of the researchers, said, "What worries me most is that people who take proton pump inhibitors, but don't actually need them, may be more seriously harmed."
Isn't that a bit surprising? Drugs that treat stomach problems can instead cause stomach cancer and even involve the cardiovascular, kidney, and more.
But similar studies haven't been uncommon in recent years; a 2017 study, for example, found that proton pump inhibitors, were associated with a 25% increased risk of early death from any cause .
Then again, a study published the same year in the journal Gut (the official journal of the British Society of Gastroenterology) found an association between long-term use of proton pump inhibitors and a 2.4-fold increase in the risk of stomach cancer.
Not only that, but there are far more negative effects when taking proton pump inhibitor-type drugs over the long term than in the studies mentioned above.
Negative effects of acid-suppressing drugs
Increased risk of gastrointestinal infections
The microbes that inhabit the gastrointestinal tract tend to be very sensitive to their surroundings, and ingesting acid-suppressing drugs such as the proton-pump inhibitors reduces the amount of acid in the stomach, and similarly affects the amount of acid that ultimately reaches the intestines.
As the acidity of the stomach decreases, many destructive microorganisms may enter the intestine unharmed or grow unchecked in the gastrointestinal tract.
A 2017 study found that ingesting acid-suppressing drugs such as proton pump inhibitors increased the risk of Clostridium difficile (which is a parasite of the human gut, and whose overgrowth affects other bacteria in the gut, triggering inflammation) by 1.7-fold, and Campylobacter (a bacterial cause of intestinal infections) by 3.7-fold.
In 2016, a related study in Australia of more than 38,019 adults, aged over 45, found that the use of acid-suppressing drugs in the proton pump inhibitor class increased the risk of hospitalization for infectious gastroenteritis.
Causes Nutrient Malabsorption
Stomach acid is critical for the body to absorb nutrients, but many people who consume proton pump inhibitor-based acid-suppressing medications over a long period of time experience more or less vitamin and mineral deficiencies involving vitamin B12, vitamin C, iron, iron, and vitamins. B12, vitamin C, iron, magnesium, and more.
A 2013 study, for example, found that long-term use of proton pump inhibitor-type acid-suppressing drugs was associated with vitamin B12 deficiency.
The researchers explained that this was due to a lack of stomach acid, which led to weakened digestion in patients, which prevented them from absorbing vitamin B12.
Impairment of cognition
A 2016 study published in JAMA found that, compared with patients who did not use the medication, patients who routinely ingested proton-pump inhibitor-based acid-suppressing drugs had a 44% increased risk of dementia.
Another 2015 study, which assessed cognitive function in users of proton pump inhibitor-based acid-suppressing drugs, versus controls, found that PPI users had statistically significant impairments in visual memory, attention, executive function, and work and planning function.
Additionally, it has also been found that patients taking proton pump inhibitor-based acid-suppressing medications have an overgrowth of enterococci in the intestines, which may be transferred to the liver and exacerbate inflammation, triggering liver damage and exacerbating chronic liver disease. chronic liver disease .
Despite all the potential negative effects on the body, there's still a love and dependence on the proton pump inhibitor class of acid-suppressing medications, and that's because a lot of people do feel that their acid reflux improves when they take them.
But are proton pump inhibitors really that effective for gastrointestinal disorders? The first thing you need to know is that you can't just take it and leave it at that. The answer is: no.
The Proton Pump Inhibitors work by reducing the amount of acid you produce, which in turn reduces the amount of acid you need to produce to relieve the symptoms of acid reflux.
This gives everyone the illusion that acid reflux is caused by too much stomach acid, but is it really?
In fact, not many people will really have too much acid, except for some special cases:
For example, Zollinger-Ellison syndrome (Zollinger-Ellison syndrome), tumors cause excessive secretion of stomach acid, which is very rare.
For normal people, the amount of stomach acid decreases with age.
A foreign doctor did statistics, since 1976, more than 90% of patients with heartburn, digestion, flatulence, acid reflux and so on, after testing, found that there is a lack of gastric acid.
And the current medical guidelines do not measure stomach acid at all, to most people with acid reflux, directly is to eat PPI proton pump inhibitors (omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, etc.) and other acid suppression drugs.
After ingesting these drugs, you can see the efficacy in the short term, because they are really effective in inhibiting the production of gastric acid, and the effect is still very good, and in this case, you may indeed not regurgitate stomach acid.
But too little stomach acid on a regular basis , which can lead to stomach cancer, stomach ulcers, depression, intestinal stress syndrome, autoimmune diseases, asthma, and so on.
Trivia: Stomach acid has several important roles:
Breaks down proteins into digestible forms
Inhibits the growth of microorganisms that enter the body through the food, preventing infections
Properly absorbs many minerals such as calcium, magnesium, zinc, and manganese
Sends a signal when the food (known as chow) is ready to leave the stomach and enter the small intestine to continue digestion
But if acid reflux isn't caused by too much stomach acid, what is it caused by? Is there any way to really get to the root of the problem?
The Real Causes of Acid Reflux and Ways to Improve It
When we eat, food travels through the esophagus, passes through a valve - the lower esophageal sphincter (LES) - and subsequently enters the stomach, which is filled with stomach acid.
Normally, the sphincter is open when you eat and swallow, and closes when you stop eating.
For a normal person, no matter how much stomach acid you have, it won't reflux into the esophagus because the sphincter closes normally.
However, the sphincter of a person with acid reflux, which doesn't close properly, causes acid to reflux into the esophagus, which is very fragile and can't resist the powerful stomach acid, and in the long term, this can lead to very serious illnesses such as esophageal cancer.
In fact, doctors know the reason: poor closure of the sphincter , leading to acid reflux.
So just suppressing the acid may temporarily relieve the problem, but it doesn't address the root cause of the sphincter closure.
But what exactly causes a poor sphincter closure? One of the top causes comes from the foods you eat .
When you ingest certain foods, you colonize a lot of gut bacteria (gas-producing bacteria), and these gut bacteria ferment the food, which produces a lot of gas.
If, too many gas-producing bacteria colonize the intestines, a lot of gas can be produced, creating a lot of pressure, and this pressure can travel all the way up to the stomach, which can eventually "push open" the sphincter muscle gate, causing acid reflux.
That is to say, when you bring down the intake of these kinds of foods, there's a little less gas produced by bacterial fermentation, there's a little less air pressure, and the sphincter is able to close the gates, and the acid doesn't reflux back up into the esophagus, and acid reflux naturally goes away.
And most of the foods that cause this kind of problem are high-carbohydrate, or diffuse foods, or foods that your body doesn't tolerate.
The natural way to improve your acidity:
Changing your diet, such as lowering your intake of high-carb foods, or avoiding fattening foods.
Boosting your acid levels (yes, you read that right, boosting your acid levels) enhances your digestion, which in turn helps you digest as many intolerant foods as possible and reduces the likelihood that they'll run rampant in your gut.
Gastrointestinal disorders are very common, a little bit of bad food may be frequent gas production, and even difficult to 1 or 2 days, and some people are often tired of months of gastrointestinal weakness.
Therefore, the proton pump inhibitor class of drugs that can immediately relieve the symptoms has become a lot of people's "baby", but this kind of drug is only a symptomatic treatment not to treat the root cause.
If you're just treating the symptoms, long-term use of these medications can also lead to a number of negative effects, from stomach cancer to cardiovascular disease
. cardiovascular disease , kidney disease to nutritional malabsorption , impairment of cognition and more . And so on, it's a drug that has more to offer than it's worth.
If you want to relieve acid reflux and other similar diseases, first of all, you have to correctly recognize the stomach acid, which plays a significant role in the human body, help you digest a lot of difficult to digest food, help you absorb some of the micronutrients, and so on.
And, as we get older, the amount of acid produced will naturally decrease, so it's more important to learn to protect it than to suppress it.
Furthermore, to get to the root of GERD symptoms, you have to work on the foods you eat, such as the high-carb foods mentioned in the article, and then foods such as fattening foods.
Finally, the team that worked on the latest study in the article also cautioned that if you have to take a proton pump inhibitor, it's best not to do so for more than 14 days in a low-dose state .
If it is a chronic gastric disease, I think it is necessary to pay special attention to diet, as long as the control of diet, timely medication, or a long time without relapse.
Commonly used medicines for stomach disease are:
Omeprazole, Meier in, aluminum sulfate tablets, gastroenterology Kang capsule, gastric Kangling, amoxicillin and so on, which are all western medicines.
It is an effective treatment for gastric problems, which reduces the symptoms of stomach pain and facilitates the recovery of the patient's stomach.
If you eat western medicine is more hurt stomach, then take Jin Wei Tai, Jin Wei Tai treatment of gastric disease effect is still relatively good, there is no side effect, is more suitable for long-term conditioning use.
How to manage the stomach disease in life
(1) It is recommended to eat less and more meals, if it is not yet time to eat, you can add some food, but should not be too much, it must be remembered that this is not the main meal, the main meal is still to be eaten according to the normal.
(2) The food of patients with chronic gastritis is mainly soft and loose, some of the more tough and crisp things should not be eaten more, because these things are the most difficult to digest.
(3) two or three hours before going to sleep, it is best not to eat, otherwise it is easy to affect the sleep, if you feel empty stomach can drink more water.
(4) Quit smoking, alcohol, coffee, strong tea, carbonated drinks.
(5) There are some vegetables and fruits that the human body can not lack of food, so it should be enough. But it is best to cook a little softer before eating, so that the stomach will feel better. Vegetables and fruit peel more fiber, you can eat in moderation, but should not be too much, not easy to digest, and thus melons and fruits can be relatively more to eat.
(6) should not exercise after meals, it is best to take a break and wait for the stomach to digest almost all the food and then start working, or walking slowly, but also better for digestion, in short, chronic gastritis should not work after meals.
Finally, non-acute cases, do not advocate taking Western medicine, because long-term medication have side effects, and gastric disease is a chronic disease, it is impossible to cure in the short term. If you need to, advocate going to take gold wei tai to regulate, good prescription for stomach especially effective. The cure for chronic gastritis is to rely on the "nurture", can't be rushed, can't be treated at once will be good, can only be obtained from the improvement of living habits. We all need a good stomach, good habits are necessary.
Stomach pain can not cure the stomach, is the liver and stagnant gas is wood and earth, is the liver gas rushing stomach,, so the liver and gas warm stomach is right, do gastroscopy what is the use? The first thing you need to do is to get a good look at the body, and then you'll be able to see what's going on.
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