Some components in grapefruit can inhibit the activity of liver drug enzymes, thus affecting the metabolism of drugs in the body. Therefore, grapefruit is the bane of many drugs and cannot be taken at the same time. It is best to avoid eating grapefruit or drinking grapefruit juice 3 hours and 6 hours before taking the following drugs. If you eat grapefruit while taking atorvastatin, lovastatin, simvastatin and other lipid-lowering drugs, patients are more likely to have muscle pain and rhabdomyolysis, and in severe cases, acute renal failure.

The synergistic effect of some chemical components in grapefruit and drugs may damage striated muscles. Patients taking statins should not eat grapefruit until the specific mechanism is clear. Because grapefruit itself has the function of lowering blood pressure, and the blood concentration of antihypertensive drugs such as nifedipine, nimodipine and verapamil can be increased during taking, eating grapefruit or drinking grapefruit juice will lead to a sudden drop in blood pressure, ranging from dizziness, palpitation and fatigue to severe angina pectoris, myocardial infarction or stroke.

Grapefruit will increase the possibility of dizziness and drowsiness caused by desi, midazolam and other drugs. Workers and drivers at high altitude should pay special attention to these drugs, including buspirone, triazolam, midazolam, desi epa, clonazepam and doxycycline epa. Moreover, grapefruit will hinder women from absorbing birth control pills. If women who take birth control pills eat grapefruit after sex, it may lead to contraceptive failure, and grapefruit will also have an impact? Viagra? Generally, users of Viagra will take Viagra 1 0 hours before having sex, but if they take it with grapefruit, the effective time of Viagra will be greatly delayed.

Grapefruit may cause adverse reactions of antiallergic drugs, such as terfenadine, diarrhea, dizziness, nausea, muscle pain, abnormal liver function and arrhythmia. And it will also aggravate the influence of anti-allergic drugs on the heart and the adverse reactions of the liver and gastrointestinal tract. Grapefruit can increase the concentration of immunosuppressants such as cyclosporine in blood and increase the toxicity of liver and kidney. If this medicine is taken with grapefruit and other fruits for a long time, it may cause tumors.