Preparation of water pills Water pills are prepared by pan-method. There are two methods of pan-pill making: manual pan-pill making and mechanical pan-pill making. Their operating principles are the same, mainly including raw material processing and crushing, demoulding, forming, covering surface selection, drying, coating, polishing and quality inspection. Among them, demoulding is the key step. 1.Processing and crushing of raw materials: all the medicines in the prescription are processed according to requirements, crushed and sieved by 100 mesh for later use. 2. Mold removal: Pill mold is the basis of pan-shot molding. There are two methods: post-construction and mechanical demoulding. (1) Manual demoulding: on the clean and dry bamboo plaque 1/4, apply a brush with a little water to make the plaque surface wet, sprinkle a little powder on the wet plaque surface, hold the plaque with both hands, rotate the bamboo plaque to make the medicine all wet, and then gently brush it down with the brush (that is, gently adjust it with the brush tip), and rotate the bamboo plaque. Uniformly coat all the small particles with the powder and shake them to another place, then apply a small amount of water to the original water-coated place, then move the powder-coated particles to the water-coated place and roll, then dip all the water, then transfer to another dry place, sprinkle with fine powder, and then rotate the bamboo plaque to roll all the wet particles with the powder. This operation is repeated for many times until a relatively dense small round particle is formed (for example, the size and diameter are about 0.5- 1mm) (2) Mechanical demoulding: spreading the powder in the coating pot, spraying water under the rotation of the coating pot, so that the powder is all wet small particles, adding a small amount of fine powder, rolling for a certain period of time, spraying water to make the small particles firm and dense, and repeating the operation, that is, forming a regular pill mold, and then continuing molding after screening (or pouring an appropriate amount of water into the pot first, and then adding an appropriate amount of powder, and then. 3. Enlarge molding: after the mold is made, rotate the bamboo plaque repeatedly, add water and powder alternately, and rotate the medicine plaque continuously. The whole basic action is kneading, knocking over and alternating, so as to strengthen the hardness and roundness of the pellets until the pellets are gradually enlarged and molded to meet the requirements. (Manual and mechanical are the same) 4. Pill selection: use a suitable medicine sieve to screen the pills evenly, and the pills that are too small will become bigger, and the ones that are too big and deformed should be separated for proper treatment. 5. Covering: The purpose of covering is to make the surface of pellets compact, smooth and uniform in color. There are three commonly used methods: dry powder cover, clear water cover and clear slurry cover. 6. Drying: due to the large amount of water in water pills, it should be dried in time (below 60 degrees). When drying, the temperature should be gradually raised, and it should be turned constantly, so as to avoid producing yin and yang. The second part: 1. Mother pill: Mother pill is the basic particle of pan pill and the key to making water pills. First, spray or smear a little cold boiled water on the medicine plaque (water pill sieve), then sprinkle a little powder to make the powder wet and adhere evenly, then brush it down slowly with a dry brush to form fine wet particles, and then add a little powder to make the particles gradually round with the swing of the medicine plaque. Repeat the operation of spraying water and adding powder for about 20 times, and fine pills appear. 2. Pilling: Take the mother pill and repeat the operation in the tablet according to the above method, add the powder and binder, and it will be made into a Chinese pill with the size of perilla for about 20 times, and then it will be made into a water pill with the standard size after 100 times. Pay attention to the swing of the medicine plaque, and make sure that the surface of the water pill is smooth and uniform in size. Third, drying: the prepared water pills should be dried at low temperature in time, and those containing aromatic drugs should only be placed in a ventilated place to dry in the shade. 4. Coating polishing: If coating is required, wet the dried water pills with appropriate liquid, add coating materials for spin coating, and then dry at low temperature. For those who need polishing, use rotary polishing to make the surface of pills moist and shiny. 5. Packaging: Water pills are placed in closed containers or plastic bags to prevent moisture, high temperature and pests. Pay attention to the time: 1. Starting the mother pill is the key to making water pills. The mother pill requires uniform size and neat shape. Sticky medicinal materials are not easy to get pregnant, so you can prescribe drugs with low viscosity to get pregnant, such as licorice. Second, in the process of starting the mother and pan-pill, water should be added appropriately. The powder containing more viscosity needs less water, and the powder containing more fiber needs more water. Third, in order to make the water pills uniform in particle size, it is necessary to pay attention to the screening of the pills if they are too small. Fourth, the rotation should be appropriate when the pills are pan-rolled. If the rolling time is too long, the pills are too tight and not easy to disintegrate, and the rolling time is too short, and the pills are loose and easy to crack. Five, pan pill operation should be continuous, can't put dry and then increase, otherwise easy to peel off. You can master the production method by synthesizing it.