The toxicity of nicotine can be divided into the following four categories:

1, which can lead to your chronic poisoning: nicotine is a highly toxic substance, and the oral LD50 of nicotine in rats is 50mg/kg, and that in mice is 3.3 mg/kg.

Nicotine in one cigarette can poison a mouse, and nicotine in 20 cigarettes can poison a cow. If a person smokes a large amount of nicotine at a time (50 to 70 mg, equivalent to the nicotine content of 40 to 60 cigarettes), it may lead to death.

2. It will also hinder the treatment of chemotherapy: In April 20 13, a study published by American researchers showed that nicotine can prevent chemotherapy drugs such as paclitaxel from killing lung cancer cells, which may help explain why lung cancer patients who smoke are very difficult to treat.

3. Increased incidence of cancer: The smoke produced by cigarette burning contains at least 2000 harmful components, such as benzopyrene, benzoanthracene, nitrosamines, polonium 2 10, cadmium, arsenic, β-naphthylamine, etc. , with carcinogenicity, carcinogens in cigarette smoke include cyanide, o-cresol, phenol, etc.

Under the synergistic effect of carcinogens and cancer promoters, normal cells will be damaged and form cancer.

Extended data:

Nicotine can make people addicted or dependent, and repeated use of nicotine can also increase heart rate, blood pressure and appetite. Large doses of nicotine can cause vomiting and nausea, and in severe cases people will die.

Tobacco usually contains nicotine. E-cigarettes also contain nicotine, a harmful substance of traditional tobacco.

References:

Baidu encyclopedia-nicotine