How should mild thalassemia be treated?
Is treatable. This is a genetic defect that cannot be cured unless the gene is changed. 1. General treatment should pay attention to rest and nutrition, and actively prevent infection. Appropriate supplementation of folic acid and vitamin E. Blood transfusion and iron removal are still one of the important treatment methods at present. A small amount of red blood cell infusion is only suitable for moderate α and β thalassemia, not for severe β thalassemia. For severe β thalassemia, medium and large doses of blood transfusion should be given from the early stage to make the growth and development of children close to normal and prevent bone lesions. The methods are as follows: firstly, the concentrated red blood cells are infused repeatedly to make the hemoglobin content of children reach120 ~150g/L; Then, every 2 ~ 4 weeks, concentrated red blood cells 10 ~ 15 ml/kg were infused to keep the hemoglobin content above 90 ~105 g/L. However, this method is easy to lead to hemosiderosis and should be treated with iron-Austrian mixture at the same time. 3. Desferriamine is commonly used in iron chelating agents, which can increase the excretion of iron from urine and feces, but it can't prevent the gastrointestinal tract from absorbing iron. Iron load is usually evaluated after regular infusion of red blood cells 1 year or 10 ~ 20 units. If there is iron overload (such as SF >;; 1000 μ g/l), using iron chelating agent. Every night, deferoxamine was injected subcutaneously for 65438 0 times, lasting 65438 02 hours, or added into isotonic glucose solution for 8-65438 02 hours; 5 ~ 7 days a week, long-term application. Or adde into red blood cell suspension for slow infusion. Deferamine has few side effects and occasional allergic reactions, which can cause cataracts and long bone development disorders for a long time. Too much will lead to poor eyesight and hearing. The combined application of vitamin C and chelating agent can enhance the effect of deferoxamine on urinary iron excretion, and the dose is 200rng/ day. Colla Corii Asini is a traditional blood-enriching formula in China, and ferrous lactate is a good bivalent iron-supplementing preparation. Many blood-enriching products on the market are used as a formula alone. Tiezhiyuan tablet contains ferrous lactate, colla Corii Asini and protein zinc as effective components, which has triple effects of supplementing iron, promoting blood production and nourishing, and can better prevent and improve anemia and enhance human immunity. Many thalassemia patients develop abnormally in adolescence, because excessive iron load in the body not only damages the endocrine glands that control development, but also damages the gonads themselves (boys' testicles or girls' ovaries), which usually happens to those patients who have not received perfect treatment in the early stage. However, most thalassemia patients who receive complete treatment for life can grow normally and have normal sexual development during adolescence. The sooner you start treatment, the better your chances of having a normal adolescence.