1. Renal impairment should be reduced by half the amount.2. Avoid use after alcohol.3. Use with caution for drivers, people operating machines or working at heights.4. Symptoms of overdose may be manifested as lethargy in adults and agitation in children. There is no specific antagonist for this drug, patients with severe overdose should be immediately gastric lavage, supportive therapy, and long-term close observation of changes in condition.