Does anyone know the efficacy of the Chinese herb Hemerocallis, especially in the treatment of lung cancer? Not half lotus oh~~
The whole grass of half lotus of the plant in the genus Eryngium. Its flavor is pungent, slightly bitter, flat. Functions for clearing heat and detoxification, diuresis and swelling. The main treatment for poisonous snake bites, boils, edema, jaundice and other diseases. [Composition and pharmacology] There are 19 species of plants in the genus Helianthus annuus in China, and 13 species are available for medicinal use. Half lotus mainly contains half lotus alkaloids (also known as sambucus alkaloids), followed by a variety of alkaloids such as dehydrosemiline (sambucus ketone alkaloids), hydrogenated sambucus alkaloids (sambucus alcohol alkaloids), as well as flavonoids, chrysanthemum sugar, sodium succinate, fenugreek acid, sodium p-hydroxybenzoate and phenolics, and so on. It also contains saponins, amino acids and so on. Animal tests have proved that hemiptera has a certain anti-tumor effect. Tests have confirmed its inhibitory effect on mouse sarcoma 37 cells. Hemipterocarpine can inhibit the oxygen uptake of mouse ascites cancer cells. In addition to antitumor effect, hemicarpine alkaloids have central excitatory effect, is an important neurocholine receptor agonist, it also has diuretic, choleretic, anti-bacterial, anti-inflammatory, anti-snake venom and other pharmacological effects. [Modern Application] Clinical Guangzhou, half of the lotus is used in the treatment of various cancers, with the compound application as much. 1. Hepatocellular carcinoma combined with ascites Lin reported that 21 cases of primary hepatocellular carcinoma combined with ascites were treated. Based on the method of activating blood circulation and inducing diuresis, 30g of half lotus was reused for each vice, supplemented with western medicines and symptomatic treatment and other measures at the same time. Results: 15 cases with obvious effect (ascites subsided, symptoms improved), 4 cases with effective effect (ascites reduced, symptoms stabilized or improved), and 2 cases with ineffective effect. Lin also reported that 44 cases of middle and advanced primary liver cancer were treated with Fuzheng Soft Kin Method. For patients with ascites or lower limb edema, water-inducing traditional Chinese medicine was used on the basis of Fuzheng Soft Firmness, and 30g of Semen Ziziphiroxylon was reused, which was proved to be effective in improving patients' hypothermia, dyspareunia, hepatic disease, abdominal distension and alleviating ascites. The survival rates of half year, 1 year, 3 years and more than 5 years after treatment were 77.3%, 59%, 15.9% and 6.8% respectively. 2.Lung Cancer Yu reported that 30 cases of advanced lung cancer were treated. On the basis of dialectical evidence, 30g of Semen Ziziphiroides was added to each type of lung cancer, which was taken by decoction with water in 1 side per day and Xihuang Pill was also added to the treatment. Treatment results: prolonged survival 4-6 months in 17 cases, 6-12 months in 5 cases, 1-2 years in 5 cases, 2-3 years in 3 cases. Zhang reported that 34 cases of advanced primary lung cancer in the elderly were treated by identification and typing, and each type was selected and added with anticancer drugs such as hemicranium, decoction was given as 1 dose per day, and the treatment lasted 4 months. Results: 1 case of partial remission, 30 cases of stabilization, 3 cases of deterioration. There were 27 cases surviving for 1 year, 6 cases for more than 1 year, 1 case for more than 2 years, and 6 cases died. In addition, hemiflora has been reported in the treatment of colorectal cancer, nasopharyngeal cancer, esophageal cancer, gastric cancer, myeloma, brain tumor and so on. For example, Gao's reported that half lotus was used to treat colorectal cancer with single flavor, and achieved better curative effect. Luo reported that 95 cases of nasopharyngeal carcinoma were treated with combination of Chinese and western medicine. The three-step treatment method was adopted, in which White Lotus Antidote Soup (White Flower Snake Tongue Herb, Half Lotus, Half Lotus, etc.) was used for internal use in the radiotherapy stage, and White Lotus Antidote Soup was also used for the type of yin deficiency and fire exuberance after the radiotherapy, and the treatment was supplemented with corrective and consolidation treatment in the later stage. Results: 42 cases within 5 years of survival, accounting for 44.4%; 38 cases from 5 to 10 years, accounting for 40%; 15 cases more than 10 years, accounting for 15.6%. The total survival rate of more than 5 years was 55.6%. There were 13 cases of recurrence and 6 cases of metastasis to other organs. Zhou reported that 32 cases of esophageal cancer and 18 cases of gastric cancer were treated with the basic formula of soup and half-bordered lotus compound (Codonopsis pilosulae, Astragalus membranaceus, Poria cocos, half-bordered lotus, white-flowered snakeroot, etc.) plus Huqi san for internal use, 1 dose per day. Results: 2 cases with survival or more than 6 years (calculated from the treatment date), 4 cases with 3-6 years, 5 cases with 2-3 years, 25 cases with 1-2 years, 10 cases with 6-12 months, 4 cases with less than 6 months, obtaining better therapeutic effect. Liu reported that 10 cases of multiple myeloma were treated with chemotherapy and traditional Chinese medicine. The medicines were used to take the compound formula of hemiptera (Xianhe Cao, hemiptera, hemiptera, white-flower snakeweed, etc.) internally. Treatment results: 6 cases survived at present, including 2 cases with obvious effect, 3 cases with remission, 1 case with no change, and the longest has survived for 5 years; 1 case died. Liu reported that 100 cases of postoperative patients with malignant tumors of central nervous system were treated with Tumor No. I and Tumor No. II formulae, which were compound formulae composed of antitumor Chinese medicines such as Hemerocallis fulva. Results: 15 cases were clinically cured, 28 cases showed obvious effect, 26 cases were effective, 36 cases were ineffective, and the total effective rate was 64%. There was no obvious difference between No.I and No.II formula in terms of efficacy. [Toxic side effects] general dose of half lotus preparation by animal experiments, on body weight, urine sediment and urine protein examination are no abnormal findings, pathological examination also did not see significant organic changes. Clinical half of the lotus decoction orally, even if long-term application, also did not see obvious toxic reactions. This may be related to its slower absorption and faster elimination. Because of the sanguinarine-like effect, so the hemicarpine preparation injection, a few cases have dizziness, sweating and other reactions. When hemicarpine injection is given in overdose, it can cause serious reactions such as tachycardia, conduction block, vomiting, convulsions, drop in blood pressure and even respiratory paralysis. However, because of its short duration of action, fewer people are really in danger.