(1) At present, there are mainly H2 receptor antagonists (H2-RA) and proton pump inhibitors (PPI) in clinic. PPI is the first choice for treating duodenal ulcer because of its faster healing rate and higher healing rate. Commonly used PPI includes omeprazole, pantoprazole, lansoprazole, rabeprazole, esomeprazole, eprazole, etc.
(2) Mucosal protectant combined with gastric acid inhibitor can improve the quality of ulcer healing and reduce ulcer recurrence.
(3) Gastrointestinal motility drugs are mainly used for patients with nausea, vomiting, abdominal distension and other symptoms to promote gastrointestinal emptying and relieve symptoms.
(4) Eradication of Helicobacter pylori