A single intravenous dose of this product containing 100 mg of iron was given to a healthy volunteer, and iron levels reached a maximum after 10 min, averaging 538 mmol/l. The central compartment volume of distribution was equal to the plasma volume (approximately 3 L). The injected iron is rapidly cleared from the plasma with a half-life of approximately 6 h. The steady-state volume of distribution is approximately 8 L, indicating that the iron is poorly distributed in body fluids. Since the product is less stable than transferrin, a competitive exchange of iron to transferrin can be seen. The resultant iron transfer rate was 31 mg iron/24 h. Renal clearance of iron in the first 4 h after injection of this product was less than 5% of the total clearance. After 24h, plasma iron levels decreased to pre-injection iron levels and approximately 75% of the sucrose was excreted.