: ① pseudo-thrombocytopenia: due to inaccurate platelet counting, or in the use of EDTA as an anticoagulant, platelets are easily clumped, counting the number of platelets appeared "artificial" reduction in the number of platelets, the mechanism is related to the anticoagulant-dependent platelet agglutinin. ② insufficient platelet production: see the application of myelosuppressive drugs, radiation, aplastic anemia and other factors that damage the hematopoietic stem cells or megakaryocytes; abnormal proliferation of bone marrow hematopoietic precursor cells, such as acute leukemia, etc.; megaloblastic anemia, platelets are ineffective hematopoiesis, insufficient platelet production. ③ Excessive platelet destruction: common in immune thrombocytopenic purpura and platelets are overconsumed diseases such as thrombotic thrombocytopenic purpura, disseminated intravascular coagulation. ④ Abnormal distribution of platelets in the body: mainly seen with the spleen and caused by the reduction in the number of platelets. Clinically, thrombocytopenic purpura can be divided into two major categories: idiopathic and secondary.

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