First, symptoms and signs This disease often has no conscious symptoms, and some patients may have local pain or itching. Occasionally it can be transformed into squamous cell carcinoma. The chief complaints of male [surname] patients may include itching, bleeding after trauma and rubbing, and odor after infection caused by wart. Clinical common diseases become papules, keratotic [surname] spots, nipple-like or vegetable-like vegetation, scattered or scattered.