High platelets can be caused by many conditions, but generally there are two conditions: ⑴ Physiological. Normal people’s platelets usually change 6-10 times a day, which are lower in the morning and lower in the afternoon. It is slightly higher; it is lower in spring and slightly higher in winter; it is higher in plateau areas; it increases after menstruation; it increases after exercise. ⑵ Pathological myeloproliferative diseases, essential thrombocythemia, acute hemolysis, acute purulent infection, etc. can all cause elevated platelets.
In other circumstances, platelets may also be elevated. For example, a person's inflammatory reaction under the action of certain inflammatory factors can lead to an increase in platelets, while other values ??are normal. The normal platelet content in human blood is 100-300×109/L, which is slightly higher than the normal value. If other values ??are normal and there are no symptoms, there will generally be no problems. It's just that platelets are involved in coagulation, and if it's too high, it will increase the possibility of thrombosis.
There is also thrombocythemia: when the platelet count is >400×109/L, it is thrombocytosis. Essential thrombocythemia is common in myeloproliferative diseases, such as chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, etc. Reactive thrombocythemia is common in patients with acute and chronic inflammation, iron deficiency anemia and cancer. However, the increase generally does not exceed 500×109/L. After treatment, the situation will be improved and the number of platelets will soon drop to normal levels.