pseudo-ginseng contains a hepatotoxic pyrrolizidine alkaloid called by the European Food Safety Agency, which will cause endothelial damage of hepatic venules, and then the venules will be blocked, so that the blood of the liver can only enter and exit, resulting in increased portal vein pressure, liver function damage, jaundice, pleural effusion, ascites, splenomegaly and other symptoms similar to "cirrhosis".
patients with mild hepatic sinus obstruction syndrome may have no obvious clinical manifestations and abnormal liver function. With the extension of taking related drugs and the increase of dosage, most patients get worse, and once this liver damage is formed, it is often irreversible. Because there is no specific treatment for the liver damage caused by taking Radix Notoginseng, if it can be found in time, the light person will stop taking it and actively treat it, and some people will recover from the liver damage, and the severe person can only undergo liver transplantation.
Extended information:
Gao Yanjing, the pharmacist in charge of the Pharmacy Department of ditan hospital, said that Panax notoginseng included in the Pharmacopoeia belongs to Araliaceae, and it is a valuable Chinese herbal medicine, which is non-toxic and can dissipate blood stasis to stop bleeding, reduce swelling and relieve pain, and can be used for hemoptysis, hematemesis, hematochezia, traumatic bleeding, chest and abdomen tingling, traumatic swelling and pain, etc.
pseudo-ginseng is a Senecio plant in Compositae. In real life, people often confuse pseudo-ginseng with pseudo-ginseng, thinking that they are different names of the same thing, but they are actually completely different drugs. Although they are similar in efficacy, they both have the effects of removing blood stasis, relieving swelling and pain, and clearing away heat and toxic materials, but they come from different families of plants, and more importantly, their toxicity is different. Panax notoginseng contains pyrrolidine alkaloids, which has strong hepatotoxicity.
Reference: People's Daily Online-Eating "Sanqi" has actually become a liver transplant expert's reminder: it is a drug with three poisons.