1, mass is the symptom of 95% breast cancer patients. Most of them are single, rare and multiple, and their shapes are round, oval or irregular. Generally, the texture is hard and the boundary is unclear. Some cases, such as medullary carcinoma, have soft texture and clear boundary. Mostly in the outer upper quadrant, the mass increases rapidly and can have activity in the early stage.

2. The common skin changes are superficial venous distension, dimple sign and orange peel skin. The chest skin of patients with inflammatory breast cancer can be darkened in large areas, showing induration and thickening, mixed with cancerous plaques and ulcers showing armor-like chest walls. Advanced breast cancer can ulcerate superficially, forming ulcers or cauliflower-like new organisms.

3, nipple areola changes breast cancer in the central area of the breast, the invasion of the large duct can cause the nipple to be flat, sunken, retracted, and even the nipple falls into a halo, resulting in areola deformation. Paget's disease can appear eczema-like changes in nipple and areola skin.

4. nipple discharge breast cancer with discharge accounts for 1.3-7% of the total breast cancer, and it is more common in intraductal carcinoma and papillary carcinoma. Bloody discharge is more common, followed by serosity, serosity and water sample. Breast cancer with discharge as the only symptom is rare, and most of them are early intraductal carcinoma and papillary carcinoma. Most breast cancer with discharge is accompanied by discharge after the tumor is found first.

5. Painless lump appears in the early stage of pain. When breast cancer is complicated with cystic hyperplasia, there may be swelling pain and dull pain. Pain in advanced breast cancer often suggests that the tumor directly invades the nerve.

6, axillary lymph node enlargement as the first symptom of breast cancer is rare (unless occult breast cancer). Most of them suggest that the course of breast cancer is progressing, and it is necessary to rule out the metastasis of other malignant tumors in upper limbs, shoulders and back and chest.

Late symptoms

First, the mass in the breast is the most important manifestation of the late symptoms of breast cancer, which generally occurs in the outer upper part of the breast. Especially, we should attach great importance to the breast masses of adult women. Breast cancer is mostly single, and it is rare to see multiple lesions in the same breast. The shape of the mass varies greatly, and it is generally considered that the shape is irregular, the edge is unclear and the texture is hard. Cancerous masses can be promoted in the breast parenchyma at an early stage, but they are not as active as benign tumors. Once they invade fascia or skin, the masses cannot be promoted, and the disease stage is later.

Secondly, breast cancer originated from glandular duct epithelium, and carcinoma in situ is difficult to find. A lump about 0.5cm is difficult to find in the deep breast, and a lump above 1cm is easy to find. There is also a rare breast cancer, occult breast cancer, whose intramammary mass cannot be found, and axillary metastasis has occurred in the late stage.

Second, the pain Most patients with early breast cancer have no obvious pain, but in the late stage of breast cancer, the pain is more obvious, and most of them are paroxysmal tingling and dull pain.

Third, nipple discharge We know that nipple discharge can be physiological or pathological. The incidence of nipple discharge during non-pregnancy and lactation is about 3%~8%. The discharge can be colorless, milky white, light yellow, brown, bloody, etc., and it can also be water sample, blood sample or serous purulent; The amount of overflow can be more or less, and the interval is different. Generally, the overflow of patients in the late stage is more serious. At this time, smear cytological examination can be carried out to make sure. Of course, most breast cancers are accompanied by breast masses. It is rare to have nipple discharge as a symptom.

Fourth, breast skin changes Breast cancer skin changes are related to the depth of the tumor and the degree of invasion. The lump is small and deep, and the skin is mostly unchanged. The lump is large and shallow, and it adheres to the skin earlier, making the skin appear depressed. If cancer cells block subcutaneous lymphatic vessels and cause skin edema, orange peel degeneration is formed, which is a late manifestation.

V. Nipple changes When there is a cancer near the nipple, the nipple is often pulled up, so the height of the bilateral nipples is different. Nipple invagination is an important sign of breast cancer in the central area. It is difficult to pull out the nipple with fingers, and the nipple is in a fixed retraction state. Eczematous carcinoma shows that the nipple is erosive and often crusted; The boundary between lesion area and skin is very clear, and the boundary between lesion area and skin is very clear, and the lesion skin is thick. Especially in patients with advanced breast cancer, these phenomena are more obvious and serious.

Sixth, breast shape changes Normal breast shape is a natural arc, and in the late stage of breast cancer, the arc is seriously abnormal. Breast cancer can generally survive for about half a year in the late stage, and it can survive normally with proper treatment.