1. Changes of oral cavity and skin mucosa: The most typical symptom in the early stage of hand, foot and mouth disease is multiple herpes or rash on oral cavity mucosa and skin of hands and feet, which is generally not accompanied by discomfort symptoms such as itching, but may have flushing.
2. Systemic symptoms: In the early stage of hand, foot and mouth disease, children generally have low fever and fever, so ibuprofen suspension should be used in time to reduce fever.
3. Throat: In the early stage of hand, foot and mouth, children may also have symptoms such as sore throat and drooling.
4. Anorexia and nausea: Because hand, foot and mouth disease is mainly caused by virus infection, virus infection may affect children's upper respiratory tract and digestive system, causing nausea, retching, anorexia, loss of appetite and other problems, and it is necessary to use some antiviral oral liquids under the guidance of doctors for treatment.