Leukemia is not necessarily caused by low platelet count, because low platelet count means that the number of platelets in the peripheral blood is lower than the normal range. Clinically, reduced platelet count can be caused by a variety of diseases, the most common of which include immunity. Thrombocytopenia, aplastic anemia, myelodysplastic syndrome, and leukemia, among others.
Leukemia is the most common malignant tumor of the blood system. Because leukemia cells proliferate disorderly in the bone marrow, normal hematopoietic function is destroyed. The patient developed a series of symptoms such as anemia, infection, bleeding, and organ infiltration.
So thrombocytopenia is not necessarily leukemia, because there are many causes of blood cell reduction, and leukemia is only one of them.
There is no clinical requirement for platelets to diagnose leukemia. The diagnosis of leukemia requires bone marrow puncture examination, and the type of leukemia requires immune typing to be clearly diagnosed.
Patients with leukemia may have normal platelets or reduced platelets, so it is not possible to judge whether it is leukemia based on the number of platelets. Generally speaking, leukemia patients will be accompanied by a decrease in the number of platelets, and the degree of decrease varies. Some have severe thrombocytopenia, which can be reduced to single digits, and some have only a mild decrease in platelets.
The blood mainly contains red blood cells, white blood cells and platelets. There are many reasons for low platelets, mainly aplastic anemia, immune thrombocytopenia, and human platelets themselves are low, so there is a link between thrombocytopenia and leukemia. There is no necessary connection between them. Leukemia is mainly a malignant proliferation tumor of white blood cells.
Generally, through routine blood examination, we will find that the white blood cells are very high. At this time, we can look at the peripheral blood smear. If the peripheral blood smear shows primitive and immature leukemia cells, then do a bone marrow examination. If the bone marrow If more than 20% of the cells are primitive or immature cells, we can diagnose acute leukemia. Therefore, there is no necessary connection between thrombocytopenia and acute leukemia. Of course, in many acute leukemias, platelets will decrease, but thrombocytopenia does not necessarily mean leukemia.
The symptoms of leukemia can be mainly divided into two categories:
1. Symptoms of suppression of normal bone marrow function:
1. Anemia
< p>It is often the first symptom and gets worse gradually.2. Fever
Half of the patients have fever as an early manifestation. Although leukemia itself can cause fever, high fever often indicates secondary infection
3. Bleeding< /p>
It can occur in various parts of the body, with skin petechiae, ecchymoses, nose bleeding, gum bleeding, and oral bleeding being the most common.
2. Manifestations of leukemia cell proliferation and infiltration:
1. Painless lymphadenopathy and hepatosplenomegaly.
2. There is often local tenderness under the sternum, and joint and bone pain may occur, which is more common in children.
3. Gingival hyperplasia and swelling, and purple-blue nodules may appear on the skin.
4. Central nervous system leukemia, headache and dizziness, and in severe cases vomiting, neck stiffness, etc.
5. Leukemia cells can also infiltrate other tissues and organs. The lungs, heart, digestive tract, urinary and reproductive systems can all be affected