Let's first look at the effects of high uric acid on gouty arthritis and tophi.
The higher the blood uric acid level and the longer the duration, the greater the possibility of urate crystal formation. Uric acid salt crystallization is the pathogenic factor of gouty arthritis. The more urate crystals are deposited, the higher the incidence of acute gouty arthritis. Relevant data show that the risk of gouty arthritis increases obviously when the blood uric acid exceeds 360 μ mol/L, and the cumulative incidence of gouty arthritis increases rapidly when the blood uric acid exceeds 480 μ mol/L.
For patients with chronic gouty arthritis, when the serum uric acid can be controlled at no more than 480 micromole/L for a long time, there are few gouty stones. When the serum uric acid exceeds 540 micromole/L, there is a 50% probability of gout stones. When the serum uric acid is between 600 and 660 micromoles per liter, most patients will form small to medium-sized gout stones. When the blood uric acid exceeds 660 micromoles per liter, a wide range of gout stones will appear.
Let's take a look at the effect of high uric acid on the kidney.
Therefore, for patients with gout, when uric acid is as high as 700, it is the best and only way to save joints and kidneys by actively reducing acid and stabilizing blood uric acid at a standard level. For asymptomatic patients with hyperuricemia, according to the relevant recommendations of gout guidelines in China, when the serum uric acid is greater than or equal to 540 μ mol/L, regardless of cardiovascular risk factors, it is necessary to start drug therapy to reduce uric acid. So uric acid is as high as 700 and there is no gout. Don't take any chances, take the medicine quickly.